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Dr. Cannabis

Cannabidiolic acid

CBDA

The raw acid form of CBD, converted to CBD by heat.

Preclinical onlyNon-intoxicating

Evidence status

Animal and in-vitro work only.

CBDA is to CBD what THCA is to THC — the acidic precursor present in the living plant, converted on heating.

Some preclinical work suggests CBDA is more potent than CBD at certain serotonin receptor targets relevant to nausea, but this has not been demonstrated in human trials.

Commonly used for

  • • Present in raw and juiced cannabis preparations

Cautions

  • • No established human evidence base.

Sources

  1. National Academies of Sciences, Engineering, and Medicine. The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research. Washington, DC: The National Academies Press, 2017.(DOI 10.17226/24625)Accessed 2026-08-15.